TRMT5 Antibody (OTI1B5)

• Reactivity: Hu
• Applications: WB, IHC
• Clone: OTI1B5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

TRMT5 Antibody (OTI1B5) Summary

• Description: Novus Biologicals Mouse TRMT5 Antibody (OTI1B5) (NBP3-44935) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-303 of human TRMT5(NP_065861) produced in E.coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: TRMT5
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000
  • Western Blot 1:2000

Packaging, Storage & Formulations

• Storage: Store at -20 degrees C. Avoid freeze/thaw cycles.
• Buffer: PBS (pH 7.3) 1% BSA, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: >95%

Alternate Names for TRMT5 Antibody (OTI1B5)

• KIAA1393EC 2.1.1.31
• M1G-methyltransferase
• TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
• TRM5MGC111453
• tRNA (guanine-N(1)-)-methyltransferase
• tRNA [GM37] methyltransferase
• tRNA methyltransferase 5
• tRNA-N1G37 methyltransferase

Background

tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 (PubMed 15248782)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRMT5