TrkC [p Tyr820] Antibody

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Western Blot: TrkC [p Tyr820] Antibody [NBP1-03448] - Rat brain lysate using Rabbit antibody to phospho Y820 TrkC: whole serum at 1:1000 dilution incubated overnight at 4 degrees C. A single band will be detected. ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

TrkC [p Tyr820] Antibody Summary

Immunogen
A synthetic peptide to phospho Y820 of human TrkC (Trk-C, NTRK3, NT-3 growth factor receptor, GP145-TrkC) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and mouse.
Modification
p Tyr820
Localization
subcellular location: membrane; single-pass type i membrane protein.; tissue specificity: widely expressed, mainly in the nervous tissue. the isoform b is expressed in a relatively large amount in the adult brain comparatively to fetal brain.
Specificity
TrkC.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NTRK3
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:300-1:3000
  • Immunohistochemistry-Paraffin 1:300-1:3000
  • Western Blot 1:300-1:3000
Control
TrkC Overexpression Lysate
Publications
Read Publications using
NBP1-03448 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Notes

The 0.1mg split size of this product is provided in liquid format (reconstituted in sterile water).

Alternate Names for TrkC [p Tyr820] Antibody

  • EC 2.7.10
  • EC 2.7.10.1
  • ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
  • ETV6-NTRK3 fusion
  • gp145(trkC)
  • GP145-TrkC
  • Neurotrophic tyrosine kinase receptor type 3
  • neurotrophic tyrosine kinase, receptor, type 3
  • NT 3 receptor
  • NT-3 growth factor receptor
  • NTRK3
  • TrkC tyrosine kinase
  • TrkC
  • trk-C
  • TRKCneurotrophin 3 receptor
  • tyrosine kinase receptor C

Background

Receptor for neurotrophin-3 (nt-3). this is a tyrosine-protein kinase receptor. known substrates for the trk receptors are shc1, pi-3 kinase, and plcg1. the different isoforms do not have identical signaling properties.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TrkC Antibody (NBP1-03448)(4)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Blogs on TrkC.

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents
Jamshed Arslan, Pharm D, PhD The dorsal root ganglia (DRG) are a collection of cell bodies of sensory nerves carrying sensory information – including nociception, mechanoreception and proprioception – from periphera...  Read full blog post.

TrkB: Bridging Ontogenesis and Oncogenesis
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. Interaction of brain-derived neurotrophic factor (BDNF) with its ...  Read full blog post.

TrkB: Docking for Neurotrophins and Beyond.
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. TrK's are activated by several neurotrophins, which are small pro...  Read full blog post.

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Bioinformatics

Gene Symbol NTRK3
Entrez
Uniprot