TrkB [p Tyr816] Antibody Blocking Peptide

• Reactivity: Rt
• Applications: AC
• Concentration: LYOPH

TrkB [p Tyr816] Antibody Blocking Peptide Summary

• Description: A NTRK2 antibody blocking peptide.
• Immunogen: A synthetic peptide from the region around (and including) phospho Y816 site of rat TrkB (BDNF/NT-3 growth factors receptor, TrkB tyrosine kinase, Trk-B) conjugated to an immunogenic carrier protein was used as the immunogen.
• Modification: p Tyr816
• Localization: subcellular location: membrane; single-pass type i membrane protein.
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: NTRK2

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-03499. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: From PBS.
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute to desired concentration using sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Notes

After reconstituted, glycerol (1:1) may be added for additional stability.

Alternate Names for TrkB [p Tyr816] Antibody Blocking Peptide

• BDNF/NT-3 growth factors receptor
• EC 2.7.10
• EC 2.7.10.1
• GP145-TrkB
• Neurotrophic tyrosine kinase receptor type 2
• neurotrophic tyrosine kinase, receptor, type 2
• NTRK2
• TrkB tyrosine kinase
• TrkB
• trk-B
• TRKBBDNF-tropomyosine receptor kinase B
• tyrosine kinase receptor B

Background

Receptor for brain-derived neurotrophic factor (bdnf), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (ngf). involved in the development and/or maintenance of the nervous system. this is a tyrosine-protein kinase receptor. known substrates for the trk receptors are shc1, pi-3 kinase, and plc-gamma-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: NTRK2