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TrkB [p Tyr816] Antibody - Azide and BSA Free

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
LYOPH

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Catalog# & Formulation Size Price

TrkB [p Tyr816] Antibody - Azide and BSA Free Summary

Immunogen
A synthetic peptide from aa region 730-821 (including phospho Y816 site) of rat TrkB conjugated to a blue carrier protein was used as the antigen. The peptide is homologous in human and mouse.
Modification
p Tyr816
Localization
subcellular location: membrane; single-pass type i membrane protein.
Specificity
TrkB.
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
NTRK2
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 10-50 ug/ml
Control
TrkB Overexpression Lysate

Reactivity Notes

Human, Rat and Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
IgG purified
Reconstitution Instructions
Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Alternate Names for TrkB [p Tyr816] Antibody - Azide and BSA Free

  • BDNF/NT-3 growth factors receptor
  • EC 2.7.10
  • EC 2.7.10.1
  • GP145-TrkB
  • Neurotrophic tyrosine kinase receptor type 2
  • neurotrophic tyrosine kinase, receptor, type 2
  • NTRK2
  • TrkB tyrosine kinase
  • TrkB
  • trk-B
  • TRKBBDNF-tropomyosine receptor kinase B
  • tyrosine kinase receptor B

Background

Receptor for brain-derived neurotrophic factor (bdnf), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (ngf). involved in the development and/or maintenance of the nervous system. this is a tyrosine-protein kinase receptor. known substrates for the trk receptors are shc1, pi-3 kinase, and plc-gamma-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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FAQs for TrkB Antibody (NBP1-03516) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for TrkB Antibody (NBP1-03516)

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Research Areas for TrkB Antibody (NBP1-03516)

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Blogs on TrkB.

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents
Jamshed Arslan, Pharm D, PhD The dorsal root ganglia (DRG) are a collection of cell bodies of sensory nerves carrying sensory information – including nociception, mechanoreception and proprioception – from periphera...  Read full blog post.

TrkB: Bridging Ontogenesis and Oncogenesis
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. Interaction of brain-derived neurotrophic factor (BDNF) with its ...  Read full blog post.

TrkB and Nervous System Function
Neutrophins and their receptors play an important role in regulating the development of both the central and peripheral nervous systems. Neurotrophin ligand binding to each of their respective Trk cellular receptors is essential for the growth and sur...  Read full blog post.

TrkB: Docking for Neurotrophins and Beyond.
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. TrK's are activated by several neurotrophins, which are small pro...  Read full blog post.

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Bioinformatics

Gene Symbol NTRK2
Entrez
Uniprot