Predicted to cross react with New World Monkey and Canine.
Alternate Names for TRIB3 Antibody
neuronal cell death inducible putative kinase
Neuronal cell death-inducible putative kinase
p65-interacting inhibitor of NF-kappaB
p65-interacting inhibitor of NF-kappa-B
TRB3chromosome 20 open reading frame 97
tribbles homolog 3 (Drosophila)
tribbles homolog 3
A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.