TRIB3 Antibody

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Western Blot: TRIB3 Antibody [NB100-56398] - Analysis of TRIB3 in human liver lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

TRIB3 Antibody Summary

Immunogen
A synthetic peptide corresponding to amino acid residues 315-332 of human TRIB3. Genbank accession number: NM_021158.
Specificity
This detects a protein of approximate mol. wt. of 40 kDa in human liver lysate.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRIB3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-3 ug/ml
  • Immunocytochemistry/Immunofluorescence
Application Notes
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Control
Human Liver Whole Tissue Lysate (Adult Whole Normal)
TRIB3 Overexpression Lysate
TRIB3 Knockout HeLa Cell Lysate
Publications
Read Publications using
NB100-56398 in the following applications:

  • 2 publications
  • WB
    3 publications

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for TRIB3 Antibody

  • C20orf97
  • dJ1103G7.3
  • neuronal cell death inducible putative kinase
  • Neuronal cell death-inducible putative kinase
  • NIPK
  • p65-interacting inhibitor of NF-kappaB
  • p65-interacting inhibitor of NF-kappa-B
  • SINK
  • SKIP3
  • TRB-3
  • TRB3chromosome 20 open reading frame 97
  • tribbles homolog 3 (Drosophila)
  • tribbles homolog 3

Background

A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRIB3 Antibody (NB100-56398)(4)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol TRIB3
Entrez
Uniprot