Human Thrombospondin-1 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human Thrombospondin-1 Quantikine ELISA Kit Summary

Background
The Quantikine Human Thrombospondin-1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Thrombospondin-1 in cell culture supernates, serum, plasma, saliva, and human milk. It contains NS0-expressed recombinant human Thrombospondin-1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Thrombospondin-1 showed linear curve...s that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Thrombospondin-1.
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Specificity
Natural and recombinant human Thrombospondin-1
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
THBS1

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DTSP10.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Thrombospondin-1 Quantikine ELISA Kit

  • THBS
  • THBS1
  • THBS-1
  • thrombospondin 1
  • Thrombospondin1
  • Thrombospondin-1
  • thrombospondin-1p180
  • TSP-1
  • TSP1thrombospondin-1
  • TSPTSP-1

Background

Thrombospondins (TSP) are secreted multidomain glycoproteins with many putative functions including modulating cell adhesion, proliferation, migration, and angiogenesis. At least five TSPs exist: TSP-1, -2, -3, -4, and cartilage oligomeric glycoprotein (COMP)/TSP-5. The family can be divided into two subgroups. The first, TSP-1 and -2, are homotrimeric molecules, each monomer containing an N-terminal/heparin-binding domain, a coiled-coil oligomerization domain, a von Willebrand factor-type/procollagen homology domain, three type 1 thrombospondin repeats (TSR), three EGF-like repeats, seven TSP type 3 repeats, and a C-terminal globular domain. TSP-1 and -2 are thought to mediate interactions between cells and the extracellular matrix, and as such are matricellular proteins. In contrast, TSP-3, -4, and COMP/TSP-5 are homopentamers that lack the N-terminal structure of TSP-1 and -2, but have a similar arrangement of EGF and TSP type 3 repeats, and the C-terminal domain characteristic of the TSP family.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Thrombospondin-1 (DTSP10)(29)

We have publications tested in 2 confirmed species: Human, Complex Species Category.


Filter By Application
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Human
(27)
Complex Species Category
(1)
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Showing Publications 1 - 10 of 29. Show All 29 Publications.
Publications using DTSP10 Applications Species
S Lie, BR Vieira, S Arruda, M Simões, LM Ashander, JM Furtado, JR Smith Molecular Basis of The Retinal Pigment Epithelial Changes That Characterize The Ocular Lesion in Toxoplasmosis Microorganisms, 2019;7(10):. 2019 [PMID: 31569536] (Human) Human
T Daubon, C Léon, K Clarke, L Andrique, L Salabert, E Darbo, R Pineau, S Guérit, M Maitre, S Dedieu, A Jeanne, S Bailly, JJ Feige, H Miletic, M Rossi, L Bello, F Falciani, R Bjerkvig, A Bikfalvi Deciphering the complex role of thrombospondin-1 in glioblastoma development Nat Commun, 2019;10(1):1146. 2019 [PMID: 30850588] (Human) Human
S Haegele, J Fuxsteiner, D Pereyra, C Koeditz, B Rumpf, C Schuetz, C Schwarz, C Brostjan, T Gruenberge, P Starlinger Elevated ADAMTS13 Activity is Associated with Poor Postoperative Outcome in Patients Undergoing Liver Resection Sci Rep, 2018;8(1):16823. 2018 [PMID: 30429491] (Human) Human
K Watt, D Newsted, E Voorand, RJ Gooding, A Majewski, P Truesdell, B Yao, T Tuschl, N Renwick, AW Craig MicroRNA-206 suppresses TGF-? signalling to limit tumor growth and metastasis in lung adenocarcinoma Cell. Signal., 2018;50(0):25-36. 2018 [PMID: 29935234] (Human) Human
S Yang, R Song, X Li, T Zhang, J Fu, X Cui Thrombospondin-2 predicts response to treatment with intravenous immunoglobulin in children with Kawasaki disease BMJ Paediatr Open, 2018;2(1):e000190. 2018 [PMID: 29637185] (Human) Human
M Mussbacher, WC Schrottmai, M Salzmann, C Brostjan, JA Schmid, P Starlinger, A Assinger Optimized plasma preparation is essential to monitor platelet-stored molecules in humans PLoS ONE, 2017;12(12):e0188921. 2017 [PMID: 29220362] (Human) Human
D Muramatsu, M Okabe, A Takaoka, H Kida, A Iwai Aureobasidium pullulans produced ?-glucan is effective to enhance Kurosengoku soybean extract induced Thrombospondin-1 expression Sci Rep, 2017;7(1):2831. 2017 [PMID: 28588201] (Human) Human
AT Amaraseker, B Assadi-Kha, S Liu, M Black, G Dymmott, NM Rogers, AL Sverdlov, JD Horowitz, DTM Ngo Vitamin D supplementation lowers thrombospondin-1 levels and blood pressure in healthy adults PLoS ONE, 2017;12(5):e0174435. 2017 [PMID: 28489857] (Human) Human
S Chandran, J Watkins, A Abdul-Aziz, M Shafat, PA Calvert, KM Bowles, MD Flather, SA Rushworth, AD Ryding Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST-Segment Elevation Myocardial Infarction J Am Heart Assoc, 2017;6(5):. 2017 [PMID: 28468787] (Human) Human
C Di Mauro, R Rosa, V D'Amato, P Ciciola, A Servetto, R Marciano, RC Orsini, L Formisano, S De Falco, V Cicatiello, M Di Bonito, M Cantile, F Collina, A Chambery, BM Veneziani, S De Placido, R Bianco Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers Br. J. Cancer, 2017;0(0):. 2017 [PMID: 28441382] (Human) Human
Show All 29 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Thrombospondin-1 (DTSP10). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DTSP10

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Bioinformatics

Gene Symbol THBS1