Human Thrombospondin-1 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human Thrombospondin-1 Quantikine ELISA Kit Summary

Background
The Quantikine Human Thrombospondin-1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Thrombospondin-1 in cell culture supernates, serum, plasma, saliva, and human milk. It contains NS0-expressed recombinant human Thrombospondin-1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Thrombospondin-1 showed linear curve...s that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Thrombospondin-1.
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Specificity
Natural and recombinant human Thrombospondin-1
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
THBS1

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DTSP10.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Thrombospondin-1 Quantikine ELISA Kit

  • THBS
  • THBS1
  • THBS-1
  • thrombospondin 1
  • Thrombospondin1
  • Thrombospondin-1
  • thrombospondin-1p180
  • TSP-1
  • TSP1thrombospondin-1
  • TSPTSP-1

Background

Thrombospondins (TSP) are secreted multidomain glycoproteins with many putative functions including modulating cell adhesion, proliferation, migration, and angiogenesis. At least five TSPs exist: TSP-1, -2, -3, -4, and cartilage oligomeric glycoprotein (COMP)/TSP-5. The family can be divided into two subgroups. The first, TSP-1 and -2, are homotrimeric molecules, each monomer containing an N-terminal/heparin-binding domain, a coiled-coil oligomerization domain, a von Willebrand factor-type/procollagen homology domain, three type 1 thrombospondin repeats (TSR), three EGF-like repeats, seven TSP type 3 repeats, and a C-terminal globular domain. TSP-1 and -2 are thought to mediate interactions between cells and the extracellular matrix, and as such are matricellular proteins. In contrast, TSP-3, -4, and COMP/TSP-5 are homopentamers that lack the N-terminal structure of TSP-1 and -2, but have a similar arrangement of EGF and TSP type 3 repeats, and the C-terminal domain characteristic of the TSP family.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Thrombospondin-1 (DTSP10)(37)

We have publications tested in 2 confirmed species: Human, Complex Species Category.


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Human
(35)
Complex Species Category
(1)
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Showing Publications 1 - 10 of 37. Show All 37 Publications.
Publications using DTSP10 Applications Species
L Oldfield, A Evans, RG Rao, C Jenkinson, T Purewal, EE Psarelli, U Menon, JF Timms, SP Pereira, P Ghaneh, W Greenhalf, C Halloran, E Costello Blood levels of adiponectin and IL-1Ra distinguish type 3c from type 2 diabetes: Implications for earlier pancreatic cancer detection in new-onset diabetes EBioMedicine, 2022;75(0):103802. 2022 [PMID: 34990893] (Human) Human
E Fernández-, C Lleixà, X Suarez-Cal, J Diaz-Maner, I Illa, E Gallardo, N de Luna Proteasome inhibitors reduce thrombospondin-1 release in human dysferlin-deficient myotubes BMC Musculoskelet Disord, 2020;21(1):784. 2020 [PMID: 33246442] (Human) Human
U Alehagen, L Shamoun, D Wågsäter Increased cardiovascular mortality in females with the a/a genotype of the SNPs rs1478604 and rs2228262 of thrombospondin-1 BMC Med. Genet., 2020;21(1):179. 2020 [PMID: 32917134] (Human) Human
M Mussbacher, TL Krammer, S Heber, WC Schrottmai, S Zeibig, HP Holthoff, D Pereyra, P Starlinger, M Hackl, A Assinger Impact of Anticoagulation and Sample Processing on the Quantification of Human Blood-Derived microRNA Signatures Cells, 2020;9(8):. 2020 [PMID: 32824700] (Human) Human
M Mussbacher, TL Krammer, S Heber, WC Schrottmai, S Zeibig, HP Holthoff, D Pereyra, P Starlinger, M Hackl, A Assinger Impact of Anticoagulation and Sample Processing on the Quantification of Human Blood-Derived microRNA Signatures Cells, 2020;9(8):. 2020 [PMID: 32824700] (Human) Human
SP Polster, A Sharma, C Tanes, AT Tang, P Mericko, Y Cao, J Carrión-Pe, R Girard, J Koskimäki, D Zhang, A Stadnik, SG Romanos, SB Lyne, R Shenkar, K Yan, C Lee, A Akers, L Morrison, M Robinson, A Zafar, K Bittinger, H Kim, JA Gilbert, ML Kahn, L Shen, IA Awad Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma Nat Commun, 2020;11(1):2659. 2020 [PMID: 32461638] (Human) Human
H Yagi, M Nishigori, Y Murakami, T Osaki, S Muto, Y Iba, K Minatoya, Y Ikeda, H Ishibashi-, T Morisaki, H Ogino, H Tanaka, H Sasaki, H Matsuda, N Minamino Discovery of novel biomarkers for atherosclerotic aortic aneurysm through proteomics-based assessment of disease progression Sci Rep, 2020;10(1):6429. 2020 [PMID: 32286426] (Human) Human
S Lie, BR Vieira, S Arruda, M Simões, LM Ashander, JM Furtado, JR Smith Molecular Basis of The Retinal Pigment Epithelial Changes That Characterize The Ocular Lesion in Toxoplasmosis Microorganisms, 2019;7(10):. 2019 [PMID: 31569536] (Human) Human
YY Joo, JW Jang, SW Lee, SH Yoo, JH Kwon, SW Nam, SH Bae, JY Choi, SK Yoon Circulating pro- and anti-angiogenic factors in multi-stage liver disease and hepatocellular carcinoma progression Sci Rep, 2019;9(1):9137. 2019 [PMID: 31235729] (Human) Human
T Daubon, C Léon, K Clarke, L Andrique, L Salabert, E Darbo, R Pineau, S Guérit, M Maitre, S Dedieu, A Jeanne, S Bailly, JJ Feige, H Miletic, M Rossi, L Bello, F Falciani, R Bjerkvig, A Bikfalvi Deciphering the complex role of thrombospondin-1 in glioblastoma development Nat Commun, 2019;10(1):1146. 2019 [PMID: 30850588] (Human) Human
Show All 37 Publications.

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Bioinformatics

Gene Symbol THBS1