TRF-2 Antibody (4A794.15) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, Rt, MaSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Clone
4A794.15
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

TRF-2 Antibody (4A794.15) [Janelia Fluor® 549] Summary

Immunogen
Baculovirus expressed whole length TRF2 protein was used for immunizing mice and splenocytes used to generate the hybridoma clone (NP_005643).
Specificity
The recognizes distinct doublet bands of approximate size 66 kDa corresponding to the molecular size of huTRF2 by western blot analysis against lysates from most human cell lines.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TERF2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Muntjac (deer) reactivity reported in scientific literature (PMID: 15878333).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TRF-2 Antibody (4A794.15) [Janelia Fluor® 549]

  • Telomeric DNA-binding protein
  • telomeric repeat binding factor 2
  • Telomeric repeat binding protein 2
  • telomeric repeat-binding factor 2
  • TERF2
  • TRBF2
  • TRF2
  • TRF-2
  • TTAGGG repeat binding factor 2
  • TTAGGG repeat-binding factor 2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB100-56506JF549
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Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for TRF-2 Antibody (NB100-56506JF549). (Showing 1 - 3 of 3 FAQ).

  1. Are the TRF-2 antibodies validated in Simple Western?
    • Yes, we offer a 2 TRF-2 antibodies that have been tested in Simple Western: NB100-56506 and NB110-57130.
  2. Does TRF-2 antibodies comes in lyophilized form?
    • we carry 2 TERF2/TRBF2 antibodies in lyophilized form: AF5635, MAB5635.
  3. What the theoretical molecular weight for TRF-2 antibodies?
    • The TMW of TRF-2 antibodies is approximately 55 - 56 kDa.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB100-56506AF350
Alexa Fluor 405 NB100-56506AF405
Alexa Fluor 488 NB100-56506AF488
Alexa Fluor 532 NB100-56506AF532
Alexa Fluor 594 NB100-56506AF594
Alexa Fluor 647 NB100-56506AF647
Alexa Fluor 700 NB100-56506AF700
Alexa Fluor 750 NB100-56506AF750
Allophycocyanin NB100-56506APC
Biotin NB100-56506B
DyLight 350 NB100-56506UV
DyLight 405 NB100-56506V
DyLight 488 NB100-56506G
DyLight 550 NB100-56506R
DyLight 594 NB100-56506DL594
DyLight 650 NB100-56506C
DyLight 680 NB100-56506FR
DyLight 755 NB100-56506IR
FITC NB100-56506F
HRP NB100-56506H
Janelia Fluor 549 NB100-56506JF549
Janelia Fluor 646 NB100-56506JF646
PE NB100-56506PE
PerCP NB100-56506PCP

Additional TRF-2 Products

Bioinformatics Tool for TRF-2 Antibody (NB100-56506JF549)

Discover related pathways, diseases and genes to TRF-2 Antibody (NB100-56506JF549). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Pathways for TRF-2 Antibody (NB100-56506JF549)

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PTMs for TRF-2 Antibody (NB100-56506JF549)

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Research Areas for TRF-2 Antibody (NB100-56506JF549)

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Blogs on TRF-2.

Application Highlight: Recent uses of TERF2 in immunofluorescence (IF)
Telomeres are a region of repeat nucleotide sequences located at the end of chromosomes to protect our DNA from becoming damaged via end-to-end fusion.  TERF2, or telomeric-repeat binding factor 2, is important for telomere integrity and aids in th...  Read full blog post.

TRF2: Telomere Maintenance and Protection
TRF2 (telomeric repeat-binding factor 2) is a homodimeric protein that binds the double-stranded 5'-TTAGGG-3' repeat in telomeres. It plays a critical role in the maintenance of telomeres, protecting telomeres against end-to-end chromosomal fusion, an...  Read full blog post.

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Contact Information

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Bioinformatics

Gene Symbol TERF2