TRAIL/TNFSF10 Antibody (55B709.3)


Western Blot: TRAIL/TNFSF10 Antibody (55B709.3) [NB100-56518] - Analysis of TRAIL in Jurkat lysate
Immunohistochemistry-Paraffin: TRAIL/TNFSF10 Antibody (55B709.3) [NB100-56518] - Analysis of TRAIL in human kidney using TRAIL antibody at 5 ug/ml.

Product Details

Reactivity HuSpecies Glossary
Applications WB, IHC-P
0.5 mg/ml

TRAIL/TNFSF10 Antibody (55B709.3) Summary

This monoclonal antibody was raised against a peptide corresponding to amino acids 17-35 of human TRAIL. This peptide sequence has been shown to be involved in TRAIL and DR5 (TRAIL-R2) interaction.
In Jurkat, a 32 kDa band, which represents a membrane bound form of TRAIL, is observed.
Predicted Species
Canine (95%), Feline (95%)
IgG1 Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS containing 0.05% BSA
0.05% Sodium Azide
0.5 mg/ml
Protein G purified


  • Western Blot 1-2 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
Read Publications using NB100-56518.

Reactivity Notes

Cross reacts with Human. Predicted to react with Canine and Feline.

Alternate Names for TRAIL/TNFSF10 Antibody (55B709.3)

  • Apo-2 ligand
  • APO2L
  • Apo-2Ltumor necrosis factor (ligand) family, member 10
  • APO2Ltumor necrosis factor apoptosis-inducing ligand splice variant delta
  • CD253 antigen
  • CD253
  • Protein TRAIL
  • TL2
  • TNF-related apoptosis-inducing ligand
  • TNFSF10
  • TRAILTNF-related apoptosis inducing ligand TRAIL
  • tumor necrosis factor (ligand) superfamily, member 10
  • tumor necrosis factor ligand superfamily member 10


Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand) (6,7). TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL3-6. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRAIL/TNFSF10 Antibody (NB100-56518)(6)

We have publications tested in 1 application: WB.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB100-56518AF405
Alexa Fluor (R) 488 Labeled NB100-56518AF488
Alexa Fluor (R) 647 Labeled NB100-56518AF647
Alexa Fluor (R) 700 Labeled NB100-56518AF700
Allophycocyanin Labeled NB100-56518APC
Biotin Labeled NB100-56518B
DyLight 350 Labeled NB100-56518UV
DyLight 405 Labeled NB100-56518V
DyLight 405LS Labeled NB100-56518V3
DyLight 488 Labeled NB100-56518G
DyLight 550 Labeled NB100-56518R
DyLight 650 Labeled NB100-56518C
DyLight 680 Labeled NB100-56518FR
DyLight 755 Labeled NB100-56518IR
HRP Labeled NB100-56518H
PE Labeled NB100-56518PE
PerCP Labeled NB100-56518PCP

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Contact Information

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Gene Symbol TNFSF10

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