TRAIL/TNFSF10 Antibody (55B709.3)


Western Blot: TRAIL/TNFSF10 Antibody (55B709.3) [NB100-56518] - Analysis of TRAIL in Jurkat lysate
Immunohistochemistry-Paraffin: TRAIL/TNFSF10 Antibody (55B709.3) [NB100-56518] - Analysis of TRAIL in human kidney using TRAIL antibody at 5 ug/ml.

Product Details

Reactivity Hu, Ca, FeSpecies Glossary
Applications WB, IHC-P
1.0 mg/ml

TRAIL/TNFSF10 Antibody (55B709.3) Summary

This monoclonal antibody was raised against a peptide corresponding to amino acids 17-35 of human TRAIL. This peptide sequence has been shown to be involved in TRAIL and DR5 (TRAIL-R2) interaction.
In Jurkat, a 32 kDa band, which represents a membrane bound form of TRAIL, is observed.
Predicted Species
Canine (95%), Feline (95%). Backed by our 100% Guarantee.
IgG1 Kappa
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1-2 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
Positive Control
Jurkat Lysate (NB800-PC2)
Read Publications using
NB100-56518 in the following applications:

  • WB
    4 publications

Reactivity Notes

Cross reacts with Human. Predicted to react with Canine and Feline.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.05% Sodium Azide
1.0 mg/ml
Protein G purified

Alternate Names for TRAIL/TNFSF10 Antibody (55B709.3)

  • Apo-2 ligand
  • APO2L
  • Apo-2Ltumor necrosis factor (ligand) family, member 10
  • APO2Ltumor necrosis factor apoptosis-inducing ligand splice variant delta
  • CD253 antigen
  • CD253
  • Protein TRAIL
  • TL2
  • TNF-related apoptosis-inducing ligand
  • TNFSF10
  • TRAILTNF-related apoptosis inducing ligand TRAIL
  • tumor necrosis factor (ligand) superfamily, member 10
  • tumor necrosis factor ligand superfamily member 10


Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand) (6,7). TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL3-6. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, IHC, Neut
Species: Hu, Mu, Rt, Ge
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu, Mu, Rt, Po, ChHa, Ma
Applications: WB, Simple Western, EM, Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, CyTOF-ready, KO
Species: Hu
Applications: WB, IHC, IHC-Fr, IHC-P, IP
Species: Hu
Applications: WB, ELISA, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
Species: Hu
Species: Hu, Mu, Rt, Ca, Ge
Applications: WB, IHC, IHC-Fr, IHC-P, IP
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr, IHC-P, IP
Species: Hu, Mu, Ca
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu, Rt, Ca, Ge
Applications: IHC, IHC-Fr, IHC-P, IP, Flow-IC
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, CyTOF-ready, ICFlow
Species: Hu, Ca, Fe
Applications: WB, IHC-P
Supplier Logo

Publications for TRAIL/TNFSF10 Antibody (NB100-56518)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Filter By Application
All Applications
Filter By Species
All Species
Showing Publications 1 - 7 of 7.
Publications using NB100-56518 Applications Species
Iurlaro R, Puschel F, Leon-Annicchiarico CL et al. Glucose deprivation induces ATF4-mediated apoptosis through TRAIL death receptors. Mol. Cell. Biol. Feb 27 2017 [PMID: 28242652] (WB, Human) WB Human
Toriyama S, Horinaka M, Yasuda S et al. A histone deacetylase inhibitor OBP-801 and celecoxib synergistically inhibit the cell growth with apoptosis via a DR5-dependent pathway in bladder cancer cells Mol. Cancer Ther. 2016 Jul 12 [PMID: 27406983] (WB) WB
Lamas B, Goncalves-Mendes N, Nachat-Kappes R et al. Leptin modulates dose-dependently the metabolic and cytolytic activities of NK-92 cells. J Cell Physiol. 2013 Jun [PMID: 23129404]
Leonardi R, Almeida LE, Rusu M et al. Tumor necrosis factor-related apoptosis-inducing ligand expression correlates to temporomandibular joint disk degeneration. J Craniofac Surg. 2011 Mar [PMID: 21403533]
Huang SC, Tsai HF, Tzeng HT et al. Lipid raft assembly and Lck recruitment in TRAIL costimulation mediates NF-kB activation and T cell proliferation. J Immunol. 2011 Jan 15 [PMID: 21160038] (WB)

WB: Fig 6 (Jurkat).Note: The specificity of the antibody was validated with TRAIL siRNA in Jurkat by WB in Fig 6. TRAIL siRNA knocked down endogeneous TRAIL expression in Jurkat by approximately two thirds.
Jin F, Liu X, Zhou Z et al. Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells. Cancer Res. 2005 Jul 15 [PMID: 16024638] (WB)

WB: 1. Caspase-3 mAb, clone 31A1067 (IMG-144A): Fig 3C, DU145 prostate adenocarcinoma cells.
Muller DB, Raftery MJ, Kather A et al. Frontline: Induction of apoptosis and modulation of c-FLIPL and p53 in immature dendritic cells infected with herpes simplex virus. Eur J Immunol. 2004 Apr [PMID: 15048704]

Reviews for TRAIL/TNFSF10 Antibody (NB100-56518) (0)

There are no reviews for TRAIL/TNFSF10 Antibody (NB100-56518). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for TRAIL/TNFSF10 Antibody (NB100-56518) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NB100-56518AF405
Alexa Fluor 488 Labeled NB100-56518AF488
Alexa Fluor 647 Labeled NB100-56518AF647
Alexa Fluor 700 Labeled NB100-56518AF700
Biotin Labeled NB100-56518B
DyLight 350 Labeled NB100-56518UV
DyLight 405 Labeled NB100-56518V
DyLight 488 Labeled NB100-56518G
DyLight 550 Labeled NB100-56518R
DyLight 650 Labeled NB100-56518C
DyLight 680 Labeled NB100-56518FR
DyLight 755 Labeled NB100-56518IR
HRP Labeled NB100-56518H

Additional TRAIL/TNFSF10 Products

Bioinformatics Tool for TRAIL/TNFSF10 Antibody (NB100-56518)

Discover related pathways, diseases and genes to TRAIL/TNFSF10 Antibody (NB100-56518). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRAIL/TNFSF10 Antibody (NB100-56518)

Discover more about diseases related to TRAIL/TNFSF10 Antibody (NB100-56518).

Pathways for TRAIL/TNFSF10 Antibody (NB100-56518)

View related products by pathway.

PTMs for TRAIL/TNFSF10 Antibody (NB100-56518)

Learn more about PTMs related to TRAIL/TNFSF10 Antibody (NB100-56518).

Research Areas for TRAIL/TNFSF10 Antibody (NB100-56518)

Find related products by research area.

Blogs on TRAIL/TNFSF10

There are no specific blogs for TRAIL/TNFSF10, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our TRAIL/TNFSF10 Antibody (55B709.3) and receive a gift card or discount.


Gene Symbol TNFSF10