Western Blot: TRAF-6 Antibody [NB100-56179] - Analysis of TRAF-6 in normal Human tissues using this antibody. TRAF6 is observed at ~66 kDa. Additional bands of lower molecular weight were seen in some cases, and may ...read more
Immunohistochemistry-Paraffin: TRAF-6 Antibody [NB100-56179] - Stained for TRAF6 using this antibody at 1:2000. Hematoxylin-eosin counterstain. A, mouse spleen. B, mouse thymus.
Immunohistochemistry-Paraffin: TRAF-6 Antibody [NB100-56179] - 1:2000. Analysis Hematoxylin-eosin counterstain. A, mouse lymph node. B, mouse bone marrow.
Hu, Mu, Rt, BvSpecies Glossary
WB, IHC, IHC-P, IP
This product is unpurified. The exact concentration of antibody is not quantifiable.
The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.