TRAF-2 Antibody

Images

 
Western Blot: TRAF2 Antibody [NBP2-20690] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: TRAF2 Antibody [NBP2-20690] - Immunofluorescence analysis of methanol-fixed Hep3B, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: TRAF2 Antibody [NBP2-20690] - Immunohistochemical analysis of paraffin-embedded AdCA, using antibody at 1:500 dilution.

Product Details

Summary
Product Discontinued
View other related TRAF-2 Primary Antibodies

Order Details


    • Catalog Number
      NBP2-20690
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

TRAF-2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human TRAF2. The exact sequence is proprietary.
Localization
Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRAF2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Mouse (83%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.64 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRAF-2 Antibody

  • E3 ubiquitin-protein ligase TRAF2
  • EC 6.3.2.-
  • MGC:45012
  • TNF receptor-associated factor 2
  • TRAF2
  • TRAF-2
  • TRAP3
  • TRAP3TRAP
  • tumor necrosis factor type 2 receptor associated protein 3
  • Tumor necrosis factor type 2 receptor-associated protein 3

Background

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-29323
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
NB100-56508
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IHC-P, CyTOF-ready, Flow-CS
NB100-56170
Species: Hu, Bv, Ca
Applications: WB, IHC, IHC-P, IP
NB100-56505
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready
NBP2-26506
Species: Hu, Mu, Rt
NB100-56654
Species: Hu, Mu
Applications: WB, IHC-P
MAB17761
Species: Hu, Mu, Rt
Applications: WB, ICC
MAB1419
Species: Hu, Rt
Applications: IHC, CyTOF-ready, ICC, ICFlow
NBP1-77077
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
DDX0131P-100
Species: Hu
Applications: Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P
H00001513-M01
Species: Hu
Applications: WB, ELISA, IHC-P
NBP2-37576
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC
NB100-317
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
NBP2-20690
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P

Publications for TRAF-2 Antibody (NBP2-20690) (0)

There are no publications for TRAF-2 Antibody (NBP2-20690).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TRAF-2 Antibody (NBP2-20690) (0)

There are no reviews for TRAF-2 Antibody (NBP2-20690). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TRAF-2 Antibody (NBP2-20690) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional TRAF-2 Products

Bioinformatics Tool for TRAF-2 Antibody (NBP2-20690)

Discover related pathways, diseases and genes to TRAF-2 Antibody (NBP2-20690). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRAF-2 Antibody (NBP2-20690)

Discover more about diseases related to TRAF-2 Antibody (NBP2-20690).
 

Pathways for TRAF-2 Antibody (NBP2-20690)

View related products by pathway.

PTMs for TRAF-2 Antibody (NBP2-20690)

Learn more about PTMs related to TRAF-2 Antibody (NBP2-20690).
 

Research Areas for TRAF-2 Antibody (NBP2-20690)

Find related products by research area.

Blogs on TRAF-2

There are no specific blogs for TRAF-2, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TRAF-2 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol TRAF2
Entrez
Uniprot