Hu, Bv, CaApplications:
WB, IHC, IHC-P, IPHost:
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
WB, IHC, IHC-P, PEP-ELISAHost:
The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis. This antibody recognizes TRAF1; human TRAF1 is a 416 amino acid protein.
|Product By Gene ID
- Epstein-Barr virus-induced protein 6
- Epstein-Bar virus-induced protein 6
- TNF receptor-associated factor 1
Research Areas for TRAF-1
Find related products by research area and learn more about each of the different research areas below.ApoptosisCancerCytokine Research
Bioinformatics Tool for TRAF-1
Discover related pathways, diseases and genes to TRAF-1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.