TCL1A Antibody

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

TCL1A Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids:AECPTLGEAVTDHPDRLWAWEKFVYLDEKQHAWLPLTIEIKDRLQLRVLLRREDVVLGRPMTPTQIGPSLLPIMWQLYPDGRYRSSDSSFWRLVYHIKIDGVEDMLLE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TCL1A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for TCL1A Antibody

• Oncogene TCL1
• Oncogene TCL-1
• Protein p14 TCL1
• T-cell leukemia/lymphoma 1A
• T-cell lymphoma-1
• T-cell lymphoma-1A
• TCL1A
• TCL1-PEN
• TCL1T-cell leukemia/lymphoma protein 1A

Background

Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TCL1A Antibody (NBP1-86958)(2)

Publications using NBP1-86958

• Andersson S, Nilsson K, Fagerberg L et al. The Transcriptomic and Proteomic Landscapes of Bone Marrow and Secondary Lymphoid Tissues. PLoS One 2014-01-01 [PMID: 25541736] (IF/IHC)
• Mansouri MR, Sevov M, Aleskog A et al. IGHV3-21 gene usage is associated with high TCL1 expression in chronic lymphocytic leukemia. Eur J Haematol 2010-02-01 [PMID: 19889012]

Bioinformatics

• Gene Symbol: TCL1A