TBX1 Antibody (OTI1C2) [PerCP]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI1C2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PerCP

TBX1 Antibody (OTI1C2) [PerCP] Summary

• Immunogen: Full length human recombinant protein of human TBX1(NP_542377) produced in HEK293T cell.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TBX1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for TBX1 Antibody (OTI1C2) [PerCP]

• brachyury
• CAFS
• CTHM
• DGCR
• DGS
• DORV
• T-box 1 transcription factor C
• T-box 1
• T-box protein 1
• T-box transcription factor TBX1
• TBX1C
• Testis-specific T-box protein
• TGA
• VCFS

Background

The T-box (TBX) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The TBX gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. TBX genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in TBX genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of TBX products has come mainly from the prototypical T/Brachyury, which is a transcription activator. The TBX genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TBX1