STAMP2/STEAP4 Antibody (418714)

Human STAMP2 transfected HEK293 human cell line was stained with Mouse Anti-Human STAMP2 Monoclonal Antibody (Catalog # MAB4626, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 418714
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

STAMP2/STEAP4 Antibody (418714) Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human STAMP2
  Met1-His459
  Accession # EAW76907
• Specificity: Detects human STAMP2-transfected NS0 cells but not irrelevant transfectants in flow cytometry.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: STEAP4
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for STAMP2/STEAP4 Antibody (418714)

• EC 1.16.1
• EC 1.16.1.-
• FLJ23153
• Six-transmembrane epithelial antigen of prostate 4
• SixTransMembrane protein of prostate 2
• STAMP2
• STAMP2DKFZp666D049
• STEAP family member 4
• STEAP4
• TIARP
• TIARPsix transmembrane prostate protein 2
• TNFAIP9
• Tumor necrosis factor, alpha-induced protein 9metalloreductase STEAP4
• tumor necrosis-alpha-induced adipose-related protein

Background

Human STAMP2, also called Steap4 or TIARP (TNF-alpha -induced adipose-related protein), is a 55 kDa, 459 aa, 6-transmembrane (TM) member of the Steap family of metalloreductases. It is induced by androgens in androgen-regulated prostate cells, and is up‑regulated during adipocyte differentiation by TNF-alpha . Full-length human and mouse STAMP2 share 80% aa identity. A 283 aa variant lacks a portion of the oxidoreductase domain and three TM domains. STAMP2 is present in the Golgi complex and early endosomes in addition to the cell surface.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STEAP4
• Uniprot:
  • EAW76907()