STAMP2/STEAP4 Antibody (418714) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 418714
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

STAMP2/STEAP4 Antibody (418714) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: NS0 mouse myeloma cell line transfected with human STAMP2
  Met1-His459
  Accession # EAW76907
• Specificity: Detects human STAMP2-transfected NS0 cells but not irrelevant transfectants in flow cytometry.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: STEAP4
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for STAMP2/STEAP4 Antibody (418714) [CoraFluor™ 1]

• EC 1.16.1
• EC 1.16.1.-
• FLJ23153
• Six-transmembrane epithelial antigen of prostate 4
• SixTransMembrane protein of prostate 2
• STAMP2
• STAMP2DKFZp666D049
• STEAP family member 4
• STEAP4
• TIARP
• TIARPsix transmembrane prostate protein 2
• TNFAIP9
• Tumor necrosis factor, alpha-induced protein 9metalloreductase STEAP4
• tumor necrosis-alpha-induced adipose-related protein

Background

STEAP4 is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. It is similar to two other members of the STEAP family, STEAP2 and STEAP3. STEAP4 promotes the reduction of both iron (Fe3+ to Fe2+) and copper (Cu2+ to Cu1+). STEAP4 is highly expressed in placenta, lung, heart and prostate tissues. Furthermore, it is over expressed in prostate cancer cells compared to normal prostate cells. STEAP4 may have a role in cell proliferation and prostrate cancer progression since over expression of STEAP4 in prostate cells significantly increases cell growth and colony formation. At least two isoforms of this protein are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STEAP4