SRD5A1 Antibody

Western Blot: SRD5A1 Antibody [NBP2-93860] - Analysis of extracts of various cell lines, using SRD5A1 . Exposure time: 90s.

• Reactivity: Mu, Rt
• Applications: WB, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

SRD5A1 Antibody Summary

• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SRD5A1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:2000
• Theoretical MW: 29 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.01% Thimerosal
• Purity: Affinity purified

Alternate Names for SRD5A1 Antibody

• 3-oxo-5-alpha-steroid 4-dehydrogenase 1
• EC 1.3.1.22
• EC 1.3.99.5,3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1
• S5AR 1
• SR type 1
• SRD5A1
• Steroid 5-alpha-reductase 1,5-alpha reductase
• steroid 5-alpha-reductase type I
• steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta4-dehydrogenase alpha 1)

Background

Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). There are 2 isoforms of the enzyme: SRD5A1 and SRD5A2 (MIM 607306).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SRD5A1