Sphingomyelin Synthase 2 Antibody (7D10)

Images

 
Western Blot: Sphingomyelin Synthase 2 Antibody (7D10) [H00166929-M08] - Analysis of SGMS2 expression in human stomach.
Western Blot: Sphingomyelin Synthase 2 Antibody (7D10) [H00166929-M08] - Western blot analysis of MGC26963 over-expressed 293 cell line,cotransfected with MGC26963 Validated Chimera RNAi or non-transfected control. Blot ...read more
Western Blot: Sphingomyelin Synthase 2 Antibody (7D10) [H00166929-M08] - Analysis of MGC26963 expression in transfected 293T cell line by MGC26963 monoclonal antibody (M08), clone 7D10. Lane 1: MGC26963 transfected ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, RNAi
Clone
7D10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Sphingomyelin Synthase 2 Antibody (7D10) Summary

Immunogen
MGC26963 (NP_689834, 2 a.a. ~ 81 a.a) partial recombinant protein with GST tag.DIIETAKLEEHLENQPSDPTNTYARPAEPVEEENKNGNGKPKSLSSGLRKGTKKYPDYIQIAMPTESRNKFPLEWWKTG
Specificity
MGC26963 (7D10)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SGMS2
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500RNAi Validation
  • ELISA
  • RNA Inhibition
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. It has also been used for RNAi validation.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Sphingomyelin Synthase 2 Antibody (7D10)

  • EC 2.7.8.27
  • phosphatidylcholine:ceramide cholinephosphotransferase 2
  • SM synthase
  • sphingomyelin synthase 2SMS2MGC26963

Background

Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SGMS2
Entrez
Uniprot