SOS1 Antibody

Images

 
Western Blot: SOS1 Antibody [NBP1-05955] - Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IPloaded) and HEK293T (T; 50 ug) cells. Antibodies: Affinitypurified rabbit anti-SOS1 antibody used ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

SOS1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1283 and 1333 of human son of sevenless ortholog 1 using the numbering given in entry NP_005624.2 (GeneID 6654).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SOS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation 2 - 5 ug/mg lysate
  • Western Blot 1:2000-1:10000
Application Notes
Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SOS1 Antibody

  • GF1GGF1
  • GINGF
  • guanine nucleotide exchange factor
  • HGFhereditary, 1
  • NS4
  • son of sevenless homolog 1 (Drosophila)
  • son of sevenless homolog 1
  • SOS1
  • SOS-1

Background

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SOS1
Entrez
Uniprot