SLC5A12 Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining in human kidney and skin tissues.. Corresponding SLC5A12 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human lymph node shows no positivity in non-germinal center cells as expected.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human small intestine shows weak to moderate membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human kidney shows strong membranous positivity in cells in proximal tubules.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human skin shows no positivity in keratinocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

SLC5A12 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: QGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRH
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC5A12
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Use in ICC/IF reported in scientific literature (PMID: 31708446).
Control Peptide
SLC5A12 Recombinant Protein Antigen (NBP2-49322PEP)
Publications
Read Publication using
NBP2-49322 in the following applications:

Reactivity Notes

Mouse, Rat (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SLC5A12 Antibody

  • Electroneutral sodium monocarboxylate cotransporter
  • Low-affinity sodium-lactate cotransporter
  • MGC52019
  • SMCT2DKFZp564G223
  • sodium-coupled monocarboxylate transporter 2
  • sodium-iodide related cotransporter
  • solute carrier family 5 (sodium/glucose cotransporter), member 12
  • Solute carrier family 5 member 12

Background

Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption oflactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximaltubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule(Gopal et al., 2007 (PubMed 17692818)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SLC5A12 Antibody (NBP2-49322)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC/IF, IHC-P.


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(1)
IHC-P
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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SLC5A12