SLC10A2 Antibody

Immunohistochemistry-Paraffin: Goat Polyclonal SLC10A2 Antibody [NBP1-20974] - (6µg/ml) staining of paraffin embedded Mouse Small Intestine. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.

Control: Goat Polyclonal SLC10A2 Antibody [NBP1-20974] - Negative Control showing staining of paraffin embedded Mouse Small Intestine, with no primary antibody.

• Reactivity: Mu, Rt
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

SLC10A2 Antibody Summary

• Immunogen: Peptide with sequence C-DETNKGFQPDEK corresponding to C-Terminus according to Uniprot Mouse NP_035518.1.
• Epitope: C terminus
• Predicted Species: Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SLC10A2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA Detection limit 1:4000
  • Immunohistochemistry 6-8 ug/ml
  • Immunohistochemistry-Paraffin 6-8 ug/ml

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SLC10A2 Antibody

• Apical sodium-dependent bile acid transporter
• ASBT
• IBAT
• ileal apical sodium-dependent bile acid transporter
• Ileal Na(+)/bile acid cotransporter
• ileal sodium/bile acid cotransporter
• Ileal sodium-dependent bile acid transporter
• ISBT
• Na(+)-dependent ileal bile acid transporter
• NTCP2
• NTCP2PBAM
• PBAM
• SLC10A2
• Sodium/taurocholate cotransporting polypeptide, ileal
• solute carrier family 10 (sodium/bile acid cotransporter family), member 2
• Solute carrier family 10 member 2

Background

SLC10A2 plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SLC10A2 Antibody (NBP1-20974)(1)

Publication using NBP1-20974

• Annaba F, Sarwar Z, Kumar P et al. Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts. Am J Physiol Gastrointest Liver Physiol 2008-02-01 [PMID: 18063707]

Bioinformatics

• Gene Symbol: SLC10A2
• Entrez:
  • 20494(Mouse)
  • 29500(Rat)
• Uniprot:
  • NP_035518.1(Mouse)