SLC5A8/SMCT1 Antibody (903502)

Images

 
MCF‑7 human breast cancer cell line was stained with Mouse Anti-Human SLC5A8/SMCT1 Monoclonal Antibody (Catalog # MAB8398, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by ...read more
HEK293 human embryonic kidney cell line transfected with human SLC5A8/SMCT1 and eGFP was stained with either (A) Mouse Anti-Human SLC5A8/SMCT1 Monoclonal Antibody (Catalog # MAB8398) or (B) Mouse IgG1 Isotype Control ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
903502
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

SLC5A8/SMCT1 Antibody (903502) Summary

Immunogen
NS0 mouse myeloma cell line transfected with human SLC5A8/SMCT1
Met1-Leu610
Accession # NP_666018
Specificity
Detects HEK293 human embryonic kidney cell line transfected with human SLC5A8/SMCT1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SLC5A8
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25 ug/10^6 cells
  • CyTOF-ready

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SLC5A8/SMCT1 Antibody (903502)

  • AIT
  • AITSolute carrier family 5 member 8
  • Apical iodide transporter
  • Electrogenic sodium monocarboxylate cotransporter
  • MGC125354
  • SLC5A8
  • SMCT
  • SMCTSMCT1
  • Sodium iodide-related cotransporter
  • sodium-coupled monocarboxylate transporter 1
  • solute carrier family 5 (iodide transporter), member 8

Background

SLC5A8/SMCT1 (Solute Carrier family 5, member 8) is a member of the solute carrier family of multi-pass membrane proteins. SLC5A8 has been shown to transport iodide by a passive mechanism. It also transports monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism. SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma (1). It may be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract.
  1. Helm, J. et al. (2012) Pancreas 41:904.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB8398U
Alexa Fluor 405 FAB8398V
Alexa Fluor 488 FAB8398G
Alexa Fluor 594 FAB8398T
Alexa Fluor 647 FAB8398R
Alexa Fluor 700 FAB8398N
Alexa Fluor 750 FAB8398S

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Bioinformatics

Gene Symbol SLC5A8
Uniprot