SIN3A Antibody

Western Blot: SIN3A Antibody [NB100-2252] - Detection of Human and Mouse SIN3A Antibody on HeLa whole cell lysate using NB100-2252. SIN3A Antibody was also immunoprecipitated using rabbit anti-SIN3A Antibody NB100-2253, NB100-2254 and another Sin3A antibody.

Immunohistochemistry: SIN3A Antibody [NB100-2252] - Sample: FFPE sections of human metastatic lymph node (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti- Sin3A used at a dilution of 1:200 (1 ug/ml). Detection: DAB

Immunohistochemistry-Paraffin: SIN3A Antibody [NB100-2252] - FFPE section of human ovarian tumor. Rabbit anti-SIN3A Antibody used at a dilution of 1:250.

Immunohistochemistry-Paraffin: SIN3A Antibody [NB100-2252] - FFPE section of mouse squamous cell carcinoma. Rabbit anti-SIN3A Antibody used at a dilution of 1:250.

• Reactivity: Hu, Mu
• Applications: WB, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

SIN3A Antibody Summary

• Description: Novus Biologicals Rabbit SIN3A Antibody (NB100-2252) is a polyclonal antibody validated for use in IHC, WB and IP. Anti-SIN3A Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human SIN3 homolog A using the numbering given in entry NP_056292.1 (GeneID 25942).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SIN3A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SIN3A Antibody

• DKFZp434K2235
• FLJ90319
• Histone deacetylase complex subunit Sin3a
• KIAA0700
• paired amphipathic helix protein Sin3a
• SIN3 homolog A, transcription regulator (yeast)
• SIN3 homolog A, transcriptional regulator (yeast)
• SIN3A
• Transcriptional corepressor Sin3a
• transcriptional co-repressor Sin3A
• transcriptional regulator, SIN3A

Background

The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SIN3A Antibody (NB100-2252)(2)

Publications using NB100-2252

• Liu, Z, Qian, M Et al. SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis. Nat Metab 2019-11-01 [PMID: 32694864] (IF/IHC, Human)
• Sun S, Liu Z, Feng Y et al. Sirt6 deacetylase activity regulates circadian rhythms via Per2 Biochem. Biophys. Res. Commun. 2019-02-16 [PMID: 30782483] (WB, Mouse)

Bioinformatics

• Gene Symbol: SIN3A
• Entrez:
  • 25942(Human)
  • 20466(Mouse)
• Uniprot:
  • Q96ST3(Human)