SIGIRR Antibody Pair

Images

 

Product Details

Summary
Product Discontinued
View other related SIGIRR Antibody Pairs

Order Details


    • Catalog Number
      H00059307-PW1
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

SIGIRR Antibody Pair Summary

Description
Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.

  • Antibody pair for IP: rabbit polyclonal anti-SIGIRR (300 ul)
  • Antibody pair for WB: mouse polyclonal anti-SIGIRR (50 ul)
  • Clonality
    Polyclonal
    Gene
    SIGIRR

    Applications/Dilutions

    Dilutions
    • Immunoprecipitation
    • Western Blot

    Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    1x PBS, pH 7.4
    Preservative
    No Preservative

    Notes

    This product is produced by and distributed for Abnova, a company based in Taiwan.

    Alternate Names for SIGIRR Antibody Pair

    • SIGIRR
    • single Ig IL-1-related receptor
    • Single Ig IL-1R-related molecule
    • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
    • single immunoglobulin domain IL1R1 related
    • Single immunoglobulin domain-containing IL1R-related protein
    • TIR8MGC110992
    • Toll/interleukin-1 receptor 8

    Background

    SIGIRR is a member of the Toll-like receptor-interleukin 1 receptor superfamily. Members of this family are defined by the presence of an intracellular Toll-IL-1R (TIR) domain. The Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SIGIRR was originally identified through database analysis and was shown to have only one Ig domain as opposed to the normal three Ig folds seen in the TIR family. Similar to ST2, another TIR family member, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor signaling. However, SIGIRR inhibits TLR-IL-1R signaling by dimerizing with TLR4, TLR5, TLR9, and IL-1R. It also associates with the down-stream TLR signaling proteins IRAK and TRAF6 in an IL-1-dependent fashion.

    Limitations

    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

    Customers Who Viewed This Item Also Viewed...

    NB100-56566
    Species: Bv, Hu, Ma, Mu, Po, Rt
    Applications: B/N, ChIP, CyTOF-ready, DB, Dual ISH-IHC, ELISA(Cap), ELISA, Flow-CS, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr,  IHC-P, In vitro, KD, KO, PAGE, Simple Western, WB
    201-LB
    Species: Hu
    Applications: BA
    M6000B
    Species: Mu
    Applications: ELISA
    NB100-56722
    Species: Ca, Hu, Mu, Rb, Rt
    Applications: B/N, DB, ELISA, Flow-CS, Flow, Func, ICC/IF, IP, In vitro, WB
    NBP2-29328
    Species: Bv, Hu, Mu, Rt, Xp, Ye, Ze
    Applications: BindInhib, B/N, ELISA, Flow, Func-Inh, IHC, In vitro, In vivo
    NB100-56583
    Species: Hu, Rb, Rt
    Applications: Flow, IHC,  IHC-P, KO, Simple Western, WB
    7625
    Species: Mu
    Applications: ELISA
    DY523B-05
    Species: Hu
    Applications: ELISA
    DCP00
    Species: Hu
    Applications: ELISA
    NBP1-81597
    Species: Hu, Rt
    Applications: ICC/IF, IHC,  IHC-P, KD, WB
    DY417
    Species: Mu
    Applications: ELISA
    NBP2-26245
    Species: Hu, Mu
    Applications: Flow, In vitro
    NBP2-24729
    Species: Ca, Eq, Hu, Pm, Mu, Pm, Rt
    Applications: B/N, CyTOF-ready, DB, ELISA, Flow-IC, Flow, Func, ICC/IF, IHC,  IHC-P, IP, In vitro, KD, Simple Western, WB
    AF3626
    Species: Mu
    Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ICC, IHC, ICFlow, Neut, WB
    6507-IL/CF
    Species: Hu
    Applications: BA
    AF5828
    Species: Hu
    Applications: ICC, Neut, WB
    NBP2-24906
    Species: Hu, Mu, Rt
    Applications: BA, DB, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr,  IHC-P, IP, PLA, Simple Western, WB

    Publications for SIGIRR Antibody Pair (H00059307-PW1) (0)

    There are no publications for SIGIRR Antibody Pair (H00059307-PW1).
    By submitting your publication information earn gift cards and discounts for future purchases.

    Reviews for SIGIRR Antibody Pair (H00059307-PW1) (0)

    There are no reviews for SIGIRR Antibody Pair (H00059307-PW1). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
    • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
    • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

    Product General Protocols

    Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

    Video Protocols

    WB Video Protocol

    FAQs for SIGIRR Antibody Pair (H00059307-PW1) (0)

    There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

    Additional SIGIRR Products

    Research Areas for SIGIRR Antibody Pair (H00059307-PW1)

    Find related products by research area.

    Blogs on SIGIRR

    There are no specific blogs for SIGIRR, but you can read our latest blog posts.

    Contact Information

    Product PDFs

    Review this Product

    Be the first to review our SIGIRR Antibody Pair and receive a gift card or discount.

    Bioinformatics

    Gene Symbol SIGIRR