SH2D1A Antibody (08) - Azide and BSA Free

• Reactivity: Hu
• Applications: ELISA
• Clone: 08
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

SH2D1A Antibody (08) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse SH2D1A Antibody (08) - Azide and BSA Free (NBP3-26884) is a monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SH2D1A (RefSeq#: NP_002342.1; Pro2-Lys97).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Mouse
• Gene: SH2D1A
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA Capture 1:250-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for SH2D1A Antibody (08) - Azide and BSA Free

• DSHP
• DSHPLYP
• Duncan disease SH2-protein
• EBVS
• FLJ92177
• IMD5
• LYP
• MTCP1
• SAP/SH2D1A
• SAPlymphoproliferative syndrome
• SH2 domain containing 1A
• SH2 domain-containing protein 1A
• SH2D1A
• signaling lymphocyte activation molecule-associated protein
• Signaling lymphocytic activation molecule-associated protein
• SLAM associated protein/SH2 domain protein 1A
• SLAM-associated protein
• T cell signal transduction molecule SAP
• T-cell signal transduction molecule SAP
• XLP
• XLPD
• XLPDFLJ18687
• XLPSH2 domain protein 1A

Background

The cytoplasmic protein encoded by the SH2D1A gene plays an essential role in controlling EBV infection. It is expressed in T and NK cells, but not in B cells or in granulocytes. SH2D1A is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD)also known as Duncan disease. XLPD is characterized by an immunodeficiency following Epstein-Barr virus (EBV)infection. Symptoms include fatal mononucleosis, hypogammaglobulinemia, pancytopenia or malignant lymphoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SH2D1A