SETDB1 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

SETDB1 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residues 1125 and 1175 of human SET Domain, Bifurcated 1 using the numbering given in entry NP_036564.2 (GeneID 9869).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SETDB1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SETDB1 Antibody [mFluor Violet 450 SE]

• ERG-associated protein with SET domain
• ESETEC 2.1.1.43
• H3-K9-HMTase 4
• Histone H3-K9 methyltransferase 4
• histone-lysine N-methyltransferase SETDB1
• histone-lysine N-methyltransferase, H3lysine-9 specific 4
• KG1T
• KIAA0067H3-K9-HMTase4
• KMT1EERG-associated protein with a SET domain, ESET
• Lysine N-methyltransferase 1E
• SET domain bifurcated 1
• SET domain, bifurcated 1

Background

The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 039;Enhancer of zeste 039 proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities. [supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SETDB1