SESN3 293T Cell Transient Overexpression Lysate Summary
| Description |
Quality control test: Transient overexpression cell lysate was tested with Anti-SESN3 antibody by Western Blots. Plasmid: pCMV-SESN3 full-length |
| Specificity |
SESN3 293T Cell Transient Overexpression Lysate(Denatured) |
| Gene |
SESN3 |
Applications/Dilutions
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles. |
| Buffer |
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Lysate Details for Array
| Type |
293T Cell Transient Overexpression |
| Protein State |
Denatured |
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for SESN3 293T Cell Transient Overexpression Lysate
Background
Sestrin 3 (SESN3) is a member of the sestrin family of proteins, which modulate peroxide signaling and antioxident defense. p53, a tumor suppressor, regulates the expression of proteins in this family. SESN3 is a promising target for selectively killing cancer cells containing high levels of AKT, a protein kinase that is hyperactivated in cancer cells. AKT is involved in cell proliferation and protects cells from apoptosis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are
guaranteed for 6 months from date of receipt.
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