RXR beta/NR2B2 Antibody (147)

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Western Blot: RXR beta/NR2B2 Antibody (147) [NB300-311]

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB
Clone
147
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

RXR beta/NR2B2 Antibody (147) Summary

Immunogen
Hinge peptide corresponding to amino acids from the mouse retinoid X receptor, beta-isotype.
Localization
Cytoplasmic (isoform beta 4) and Nuclear (isoforms beta 1 and beta 2).
Specificity
Specific for the ~48k RXR-beta protein.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
RXRB
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Application Notes
This antibody has been tested in Western blot, detecting a band ~48 kDa.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Protein G purified

Alternate Names for RXR beta/NR2B2 Antibody (147)

  • DAUDI6
  • H-2RIIBP
  • MHC class I promoter binding protein
  • NR2B2
  • NR2B2MGC1831
  • Nuclear receptor subfamily 2 group B member 2
  • RCoR-1
  • retinoic acid receptor RXR-beta
  • Retinoid X receptor beta
  • retinoid X receptor, beta
  • RXR beta
  • RXRB

Background

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR0, 1 and g), preferentially bind 9- is-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RXRB
Entrez
Uniprot