RXR beta/NR2B2 Antibody (147) - Azide Free

Western Blot: RXR beta/NR2B2 Antibody (147) [NB300-311]

• Reactivity: Mu, Rt
• Applications: WB
• Clone: 147
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide Free

RXR beta/NR2B2 Antibody (147) - Azide Free Summary

• Description: Novus Biologicals Mouse RXR beta/NR2B2 Antibody (147) - Azide Free (NB300-311) is a monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH. Accession # P28702
• Localization: Cytoplasmic (isoform beta 4) and Nuclear (isoforms beta 1 and beta 2).
• Specificity: Specific for endogenous levels of the ~48 kDa RXR beta/NR2B2 protein.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RXRB
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Application Notes: This antibody has been tested in Western blot, detecting a band ~48 kDa.
• Theoretical MW: 48 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
• Preservative: No Preservative
• Purity: Protein G purified

Alternate Names for RXR beta/NR2B2 Antibody (147) - Azide Free

• DAUDI6
• H-2RIIBP
• MHC class I promoter binding protein
• NR2B2
• NR2B2MGC1831
• Nuclear receptor subfamily 2 group B member 2
• RCoR-1
• retinoic acid receptor RXR-beta
• Retinoid X receptor beta
• retinoid X receptor, beta
• RXR beta
• RXRB

Background

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR0, 1 and g), preferentially bind 9- is-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RXRB
• Entrez:
  • 218772(Mouse)
• Uniprot:
  • P28702(Human)