SLC39A7/ZIP7 Antibody

Western Blot: SLC39A7/ZIP7 Antibody [NBP1-76504] - Analysis in mouse brain tissue lysate with antibody at 0.5 ug/mL.

Immunocytochemistry/Immunofluorescence: SLC39A7/ZIP7 Antibody [NBP1-76504] - Immunofluorescence of ZIP7 in human brain tissue with ZIP7 antibody at 20 ug/mL.

Immunohistochemistry: SLC39A7/ZIP7 Antibody [NBP1-76504] - Immunohistochemistry of ZIP7 in human brain tissue with ZIP7 antibody at 2.5 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

SLC39A7/ZIP7 Antibody Summary

• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZIP7. The immunogen is located within amino acids 20 - 70 of ZIP7.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC39A7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 1:10-1:500
• Control Peptide:

  SLC39A7/ZIP7 Peptide (NBP1-76504PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SLC39A7/ZIP7 Antibody

• D6S115E
• D6S2244EReally interesting new gene 5 protein
• H2-KE4
• HKE4Solute carrier family 39 member 7
• HLA class II region expressed gene KE4
• Ke4 gene, mouse, human homolog of
• KE4
• RING5Histidine-rich membrane protein Ke4
• solute carrier family 39 (zinc transporter), member 7
• zinc transporter SLC39A7
• ZIP7

Background

The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC39A7
• Uniprot:
  • NP_001070984(Human)