Recombinant Human RPSA Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, PA

Order Details

Recombinant Human RPSA Protein Summary

Description
Recombinant protein with GST-tag at N-terminal corresponding to the amino acids 1 - 295 of Human RPSA full-length ORF

Source: Wheat Germ (in vitro)

Amino Acid Sequence:MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRAGHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPAPEFTATQPEVADWSEGVQVPSVPIQQFPTEDWSAQPATEDWSAAPTAQATEWVGATTDWS

Details of Functionality
This protein is not active and should not be used for experiments requiring activity.
Protein/Peptide Type
Recombinant Protein
Gene
RPSA
Purity
>80%, by SDS-PAGE

Applications/Dilutions

Application Notes
This protein has not been tested for any functionality. Product may contain endotoxins and is not suitable for use with live cells.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Purity
>80%, by SDS-PAGE

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human RPSA Protein

  • 37 kDa laminin receptor precursor
  • 37/67 kDa laminin receptor
  • 37LRPNEM/1CHD4
  • 67 kDa laminin receptor
  • 67kD, ribosomal protein SA
  • 67LR
  • Colon carcinoma laminin-binding protein
  • LAMBR37 kDa laminin receptor
  • laminin binding protein
  • laminin receptor 1 (67kD, ribosomal protein SA)
  • Laminin receptor 1
  • Laminin-binding protein precursor p40
  • LAMR 1
  • lamR
  • LAMR140S ribosomal protein SA
  • LBP
  • LBP/p40
  • LRP
  • LRP/LR
  • Multidrug resistance-associated protein MGr1-Ag
  • p40
  • ribosomal protein SA

Background

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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FAQs for RPSA Recombinant Protein (H00003921-P01). (Showing 1 - 1 of 1 FAQ).

  1. How was this recombinant protein expressed and purified?
    • This protein is expressed in a cell free wheat germ system. It is purified by Glutathione Sepharose 4 Fast Flow.

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Bioinformatics

Gene Symbol RPSA