RPSA Products

Antibodies
RPSA Antibody
RPSA Antibody
NBP1-33002
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
RPSA Antibody (MLuC5)
RPSA Antibody (MLuC5)
NB200-631
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
RPSA Antibody
RPSA Antibody
NBP2-41246
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Lysates
RPSA Overexpression Lysate (N ...
RPSA Overexpression Lysate (Native)
NBL1-15579
Applications: WB
RPSA Overexpression Lysate (N ...
RPSA Overexpression Lysate (Native)
NBL1-15578
Applications: WB
Proteins
RPSA Partial Recombinant Prot ...
RPSA Partial Recombinant Protein
H00003921-Q01
Species: Hu
Applications: WB, ELISA, PA
RPSA Recombinant Protein
RPSA Recombinant Protein
H00003921-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
RPSA RNAi
RPSA RNAi
H00003921-R04
Species: Hu
RPSA RNAi
RPSA RNAi
H00003921-R03
Species: Hu

Description

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. (provided by RefSeq)

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 3921
Alternate Names
  • LAMR 1
  • LBP/p40
  • Laminin receptor 1
  • 67LR
  • LamR
  • 67 kDa laminin receptor
  • 37 kDa laminin receptor precursor
  • 37/67 kDa laminin receptor
  • laminin binding protein
  • Multidrug resistance-associated protein MGr1-Ag
  • lamR
  • Laminin-binding protein precursor p40
  • Colon carcinoma laminin-binding protein
  • p40
  • LBP
  • laminin receptor 1 (67kD, ribosomal protein SA)
  • 67kD, ribosomal protein SA
  • LRP
  • LAMR140S ribosomal protein SA
  • LAMBR37 kDa laminin receptor
  • 37LRPNEM/1CHD4
  • LRP/LR
  • ribosomal protein SA

Research Areas for RPSA

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Cytoskeleton Markers
Extracellular Matrix
Neuroscience
Stem Cell Markers

PTMs for RPSA

Learn more about PTMs related to RPSA.

Phosphorylation
Cleavage

Bioinformatics Tool for RPSA

Discover related pathways, diseases and genes to RPSA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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