ROS Antibody

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

ROS Antibody Summary

• Description: Please note, this antibody is considered to be "Innovators Grade". Innovators Grade antibodies have been validated for limited uses and require additional characterization for most new species/applications. These antibodies are directed against antigens that have limited or no commercial antibodies available for them, or for which there are limited expression data available to us. In an effort to encourage customer feedback, Novus has made these antibodies available through our Innovators Reward program. Under this program, Novus will provide you a 50% refund on the purchased product as well as a 50% discount on a future product of equal value in exchange for your new data. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence KEPHADKDFCQE corresponding to C-Terminus according to NP_002935.2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ROS1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:2000
  • Western Blot 1:100 - 1:2000
• Application Notes: WB: Preliminary experiments in human heart and skeletal muscle lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ROS Antibody

• proto-oncogene tyrosine-protein kinase ROS
• c-ros oncogene 1 , receptor tyrosine kinase
• c-Ros-1
• MCF3
• ROS
• ROS1

Background

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ROS Antibody (NBP2-26076)(1)

Publication using NBP2-26076

• Shiffman D, Ellis SG, Rowland CM et al. Identification of four gene variants associated with myocardial infarction. Am J Hum Genet 2005-10-01 [PMID: 16175505]

Bioinformatics

• Gene Symbol: ROS1
• Entrez:
  • 6098(Human)
  • 6098(Human)