Tired T cells: Hypoxia Drives T cell Exhaustion in the Tumor Microenvironment

Methamphetamine with HIV induces mitochondrial dysfunction and neuronal injury through oxidative stress

NOX2 oxidase is a potential target for broad-spectrum antiviral therapies

Crosstalk Between Oxidative Stress and Autophagy

One MAP to Navigate the Oxidative Stress, Tumorigenesis and Apoptosis Pathways?

Reactive oxygen species, ROS, are beneficially involved in many signaling pathways that control development and maintain cellular homeostasis. In physiological conditions, a tightly regulated redox balance protects cells from injurious ROS activity, altered balance leads to various pathological conditions including cancer. MAP17 is a small 17-kDa non-glycosylated membrane protein that is overexpressed in many tumors of different origins, including carcinomas.