ROR beta Antibody (SR1948) - BSA Free

Western Blot: ROR beta Antibody (SR1948) [NBP3-22118] - Western blot analysis using NBP3-22118 in HepG2 cell lysate.

• Reactivity: Hu, Mu
• Applications: WB
• Clone: SR1948
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ROR beta Antibody (SR1948) - BSA Free Summary

• Description: Novus Biologicals Rabbit ROR beta Antibody (SR1948) - BSA Free (NBP3-22118) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human ROR beta (Uniprot #: Q92753)
• Specificity: Detects endogenous levels of total ROR beta
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: RORB
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 53 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ROR beta Antibody (SR1948) - BSA Free

• NR1F2
• NR1F2nuclear receptor ROR-beta
• Nuclear receptor RZR-beta
• Nuclear receptor subfamily 1 group F member 2
• RAR-related orphan receptor B
• RAR-related orphan receptor beta
• retinoic acid-binding receptor beta
• retinoid-related orphan receptor beta
• Retinoid-related orphan receptor-beta
• ROR beta
• RORB
• ROR-BETA
• RZRB
• RZRBbA133M9.1
• RZR-BETA

Background

Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing. Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility. ROR beta binds to the monomeric response elements containing the sequence AnnTAGGTCA as a monomer. An alternatively spliced isoform, ROR beta2, has been isolated from rats, and the expression of ROR beta2 is confined to the pineal gland and retina. ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but is characterized by a different amino-terminal domain. ROR beta expression has been documented in various regions of the mouse brain. ESTs have been isolated from human tissue libraries, including cancerous human kidney and normal brain, pineal and eye.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RORB