ROBO3 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

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ROBO3 Antibody [Biotin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human ROBO3
Leu40-Ser545
Accession # Q96MS0
Specificity
Detects human ROBO3 in Western blots. In Western blots, approximately 60% cross‑reactivity with recombinant mouse ROBO3 is observed, 10% cross-reactivity with recombinant rat ROBO1 is observed, and less than 1% cross-reactivity with recombinant human (rh) ROBO2 and rhROBO4 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ROBO3
Purity
Antigen Affinity-purified
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Applications/Dilutions

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Purity
Antigen Affinity-purified
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ROBO3 Antibody [Biotin]

  • FLJ21044
  • HGPPS
  • HGPS
  • RBIG1horizontal gaze palsy with progressive scoliosis
  • retinoblastoma inhibiting gene 1
  • RIG1
  • ROBO3
  • roundabout (axon guidance receptor, Drosophila) homolog 3
  • roundabout homolog 3
  • roundabout, axon guidance receptor, homolog 3 (Drosophila)
  • Roundabout-like protein 3

Background

Members of the ROBO family are a group of highly conserved transmembrane glycoproteins that make up a small subgroup of the immunoglobulin (Ig) superfamily. They are characterized structurally by five C2-type Ig-like repeats, three fibronectin type III domains, a transmembrane region, and an intracellular domain with three (ROBO3) or four (ROBO1, 2) CC (conserved cytoplasmic) motifs. ROBO4, a fourth putative family member, has been identified, but lacks one of the three fibronectin-like domains and two of the five Ig-like domains. ROBOs are best known for their roles as receptors for the Slit family of repellent axon guidance cues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ROBO3
Entrez
Uniprot