No results obtained, Gln20 predicted. Protein identity confirmed by MS analysis of tryptic fragments.
Structure / Form
>95%, by SDS-PAGE with silver staining
<0.10 EU per 1 μg of the protein by the LAL method.
40 kDa (monomer). Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
50-60 kDa, reducing conditions
Read Publication using 7335-CD in the following applications:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS.
>95%, by SDS-PAGE with silver staining
Reconstitute at 500 μg/mL in PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Recombinant Mouse CD90/Thy1 Fc Chimera Protein, CF
Thy-1 cell surface antigen
thy-1 membrane glycoprotein
Thy-1 T-cell antigen
CD90, also known as Thy1, is an approximately 25-35 kDa glycoprotein that mediates cellular adhesion and exerts wide ranging effects in different tissues (1, 2). Mature mouse CD90 contains one immunoglobulin-like domain followed by a GPI anchor (3-5). CD90 is expressed on hematopoietic progenitor cells, neurons, and activated vascular endothelial cells (6-8). Its species-specific expression in lymphoid cells allows its use as a thymocyte and pan T cell marker in mouse but not in human (1). CD90 can form dimers and higher order multimers (9). It binds to heparin, the proteoglycan Syndecan-4, and Integrins alpha M beta 2, alpha V beta 3, and alpha V beta 5 (8, 10-13). Through these interactions, CD90 inhibits neurite outgrowth (7), promotes astrocyte adhesion (10), mediates the adhesion and extravasation of leukocytes and melanoma cells (8, 12), supports the Thrombospondin-1 induced disassembly of fibroblast focal adhesions (14), and inhibits the activation of latent TGF-beta 1, myofibroblast differentiation, and lung fibrosis (13)
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FAQs for CD90/Thy1 (7335-CD). (Showing 1 - 1 of 1 FAQ).
We are interested in CD90 antibodies that could react with dog, please let me know which products in your catalog you would recommend.
I would recommend one of theses <a href="http://www.novusbio.com/productsearch/CD90%252FThy1#fq=common_name%3A%22CD90%2FThy1%22&fq=species%3A%22Canine%22" target="_self">CD90 antibodies</a>, as these have all been validated for use with dog/canine samples.
CD90 (Cluster of differentiation 90) CD90 is a 25-35kD glycosylphosphatidylinositol (GPI)-linked glycoprotein receptor of the immunoglobulin (Ig) superfamily. It is found on murine T-cells, thymocytes, neuronal cells, granulocytic lineage-derived cells, hematopoietic stem cells, fibrobla... Read full blog post.
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Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.