Rat TIM-1/KIM-1/HAVCR DuoSet ELISA, 15 Plate

• Reactivity: Rt
• Applications: ELISA
• Conjugate: Biotin

Rat TIM-1/KIM-1/HAVCR DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Havcr1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rat TIM-1/KIM-1/HAVCR DuoSet ELISA, 15 Plate

• CD365
• HAVCR1
• HAVCR-1
• HAVCRT cell immunoglobin domain and mucin domain protein 1
• hepatitis A virus cellular receptor 1
• Kidney injury molecule 1
• KIM1
• KIM-1
• T-cell immunoglobulin and mucin domain-containing protein 1
• TIM1
• TIM-1
• TIM-1TIM
• TIM1TIMD-1
• TIMD1T-cell membrane protein 1

Background

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

Publications for TIM-1/KIM-1/HAVCR (DY3689)(5)

Publications using DY3689

• T Pelé, S Giraud, S Joffrion, V Ameteau, A Delwail, JM Goujon, L Macchi, T Hauet, F Dkhissi, O Benzakour Study of the Role of the Tyrosine Kinase Receptor MerTK in the Development of Kidney Ischemia-Reperfusion Injury in RCS Rats International Journal of Molecular Sciences, 2021-11-09;22(22):. 2021-11-09 [PMID: 34829984] (Rat)
• J Edwards, M Kowal, A VanDreel, P Lamar, W Prozialeck A Method for the Evaluation of Site-Specific Nephrotoxic Injury in the Intact Rat Kidney Toxics, 2020-01-20;8(1):. 2020-01-20 [PMID: 31968633] (Rat)
• J Cops, W Mullens, FH Verbrugge, Q Swennen, B De Moor, C Reynders, J Penders, R Achten, A Driessen, A Dendooven, JM Rigo, D Hansen Selective abdominal venous congestion induces adverse renal and hepatic morphological and functional alterations despite a preserved cardiac function Sci Rep, 2018-12-10;8(1):17757. 2018-12-10 [PMID: 30532057] (Rat)
• J Cops, W Mullens, FH Verbrugge, Q Swennen, C Reynders, J Penders, JM Rigo, D Hansen Selective abdominal venous congestion to investigate cardiorenal interactions in a rat model PLoS ONE, 2018-05-29;13(5):e0197687. 2018-05-29 [PMID: 29813081] (Rat)
• F Mohamed, NA Buckley, JW Pickering, K Wunnapuk, S Dissanayak, U Chathurang, I Gawaramman, S Jayamanne, ZH Endre Nephrotoxicity-induced proteinuria increases biomarker diagnostic thresholds in acute kidney injury BMC Nephrol, 2017-04-03;18(1):122. 2017-04-03 [PMID: 28372541] (Rat)

FAQs for TIM-1/KIM-1/HAVCR (DY3689). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Havcr1