RAPGEF5 Antibody - BSA Free

Western Blot: RAPGEF5 Antibody - BSA Free [NBP3-46797] - Human brain tissue were subjected to SDS PAGE followed by western blot with (RAPGEF5 antibody) at dilution of 1:500

• Reactivity: Hu, Mu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

RAPGEF5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit RAPGEF5 Antibody - BSA Free (NBP3-46797) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Rap guanine nucleotide exchange factor(GEF) 5. (Uniprot# Q92565)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RAPGEF5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500-1:2000
• Application Notes: Theoretical Molecular Weight is 68-75 kDa

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for RAPGEF5 Antibody - BSA Free

• GFRREPAC
• Guanine nucleotide exchange factor for Rap1
• KIAA0277M-Ras-regulated GEF
• M-Ras-regulated Rap GEF
• MRGEF
• MR-GEFrap guanine nucleotide exchange factor 5
• Rap guanine nucleotide exchange factor (GEF) 5
• Related to Epac
• Repac

Background

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAPGEF5