PTP1B/PTPN1 Antibody

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Immunoprecipitation: PTPN1 Antibody [NBP1-28691] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PTPN1 antibody NBP1-28691 used for IP at 10 ...read more

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

PTP1B/PTPN1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 275 and 325 of human protein tyrosine phosphatase 1B using the numbering given in entry NP_002818.1 (GeneID 5770).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPN1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation 10 ug/mg lysate
Application Notes
It is not recommended for western analysis.
Reviewed Applications
Read 1 Review rated 5
using
NBP1-28691 in the following applications:

Publications
Read Publication using
NBP1-28691 in the following applications:

  • IP
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PTP1B/PTPN1 Antibody

  • EC 3.1.3.48
  • protein tyrosine phosphatase 1B
  • protein tyrosine phosphatase, non-receptor type 1
  • Protein-tyrosine phosphatase 1B
  • PTP1B
  • PTP-1B
  • PTP1Bprotein tyrosine phosphatase, placental
  • PTPN1
  • tyrosine-protein phosphatase non-receptor type 1

Background

Protein-tyrosine phosphatases 1B (PTP1B) is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTP1B has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PTP1B/PTPN1 Antibody (NBP1-28691)(1)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: IP.


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Review for PTP1B/PTPN1 Antibody (NBP1-28691) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 application: IP.

Reviews using NBP1-28691:
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IP
(1)
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Images Ratings Applications Species Date Details
Immunoprecipitation PTP1B/PTPN1 NBP1-28691
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reviewed by:
Pei-Suen Tsou
IP 11/05/2012
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Summary

ApplicationImmunoprecipitation
LotA1
Pub Med IDPMC3309078
FileView PDF

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Pei-Suen Tsou
11/05/2012
Application: IP
Species:

Bioinformatics

Gene Symbol PTPN1
Entrez
Uniprot