PTP mu/PTPRM Antibody - BSA Free

Immunohistochemistry-Paraffin: PTP mu/PTPRM Antibody [NBP3-14456] - Immunohistochemistry of formalin-fixed, paraffin-embedded human retina after heat-induced antigen retrieval.

• Reactivity: Hu, Mu, Rt, Bt, Bv, Eq, Ha, Pm, Ma-Op, Pm-Or, Pm, Rb
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

PTP mu/PTPRM Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 16 amino acid peptide from internal region of human PTP mu/PTPRM.
• Epitope: Internal
• Specificity: Human PTP mu/PTPRM. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (100%), Rat (100%), Hamster (100%), Bat (100%), Primate (100%), Equine (100%), Monkey (100%), Opossum (94%), Bovine (100%), Orangutan (100%), Rabbit (100%). Backed by our 100% Guarantee.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTPRM
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: .

Reactivity Notes

Expected reactivity based on percent sequence identity: Canine (88%), Gorilla, Xenopus (81%)

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PTP mu/PTPRM Antibody - BSA Free

• EC 3.1.3.48
• hR-PTPu
• MGC166994
• protein tyrosine phosphatase mu
• protein tyrosine phosphatase, receptor type, M
• protein tyrosine phosphatase, receptor type, mu polypeptide
• Protein-tyrosine phosphatase mu
• PTP mu
• PTPRL1
• PTPRL1R-PTP-MU
• PTPRM
• receptor-type tyrosine-protein phosphatase mu
• RPTPM
• R-PTP-mu
• RPTPU

Background

PTPRM is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRM