PTP mu/PTPRM Products

Description

PTPRM is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Bioinformatics

Entrez	5797 Human
Uniprot	NP_001098714.1 Human NP_002836 Human P28827 Human
Product By Gene ID	5797
Alternate Names	EC 3.1.3.48 hR-PTPu MGC166994 protein tyrosine phosphatase mu protein tyrosine phosphatase, receptor type, M protein tyrosine phosphatase, receptor type, mu polypeptide Protein-tyrosine phosphatase mu PTPRL1R-PTP-MU receptor-type tyrosine-protein phosphatase mu RPTPM R-PTP-mu RPTPU

Research Areas for PTP mu/PTPRM

Find related products by research area and learn more about each of the different research areas below.

Protein Phosphatase