PTP mu/PTPRM Products

Description

PTP mu, a R2A receptor protein tyrosine phosphatase, is composed of an extracellular segment containing a MAM domain, an immunoglobulin domain and four fibronectin type III repeats, a transmembrane segment, and two intracellular protein phosphatase domains. PTP mu has been shown to affect cell-cell aggregation, regulate cardiac myocyte Kv1.5 channel expression, and promote neurite outgrowth of retinal ganglion cells. The human PTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer. PTP mu may be important in responses to pathological conditions associated with the loss of cell-cell interactions in the heart.

Bioinformatics

Entrez	5797 Human
Uniprot	P28827
Product By Gene ID	5797
Alternate Names	EC 3.1.3.48 hR-PTPu MGC166994 protein tyrosine phosphatase mu protein tyrosine phosphatase, receptor type, M protein tyrosine phosphatase, receptor type, mu polypeptide Protein-tyrosine phosphatase mu PTP mu PTPRL1 PTPRL1R-PTP-MU PTPRM receptor-type tyrosine-protein phosphatase mu RPTPM R-PTP-mu RPTPU

Research Areas for PTP mu/PTPRM

Find related products by research area and learn more about each of the different research areas below.

Protein Phosphatase