PTGDR Antibody (1052528) [DyLight 680]

• Reactivity: Hu
• Applications: IHC
• Clone: 1052528
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 680

PTGDR Antibody (1052528) [DyLight 680] Summary

• Immunogen: Synthetic peptide within amino acids 50-150 of the Prostaglandin D2 receptor protein sequences
  Accession # Q13258
• Specificity: Detects Prostaglandin D2 receptor immunogen in Direct ELISA.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PTGDR Antibody (1052528) [DyLight 680]

• AS1
• ASRT1
• DP
• DP1
• MGC49004
• PGD receptor
• PGD2 receptor
• prostaglandin D2 receptor (DP)
• prostaglandin D2 receptor
• Prostanoid DP receptor
• PTGDR
• PTGDR1

Background

Prostaglandin D2 Receptor is encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.