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Prostaglandin D2 Receptor is encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. [provided by RefSeq]
![Immunohistochemistry PTGDR Antibody (1052528) [Unconjugated]](http://images.novusbio.com/fullsize/mab11249_human-ptgdr-mab-clone-1052528-immunohistochemistry-299202293831.jpg)
