PTBP2 Antibody (2D10-B2) - Azide and BSA Free

Western Blot: PTBP2 Antibody (2D10-B2) [H00058155-M01] - PTBP2 monoclonal antibody (M01), clone 2D10-B2 Analysis of PTBP2 expression in IMR-32.

Western Blot: PTBP2 Antibody (2D10-B2) [H00058155-M01] - PTBP2 monoclonal antibody (M01), clone 2D10-B2. Analysis of PTBP2 expression in human brain membrane (lane 1) and human brain cortex (lane 2).

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 2D10-B2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

PTBP2 Antibody (2D10-B2) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse PTBP2 Antibody (2D10-B2) - Azide and BSA Free (H00058155-M01) is a monoclonal antibody validated for use in WB and ELISA. Anti-PTBP2 Antibody: Cited in 3 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: PTBP2 (AAH16582, 1 a.a. ~ 532 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDGIVTEVAVGVKRGSDELLSGSVLSSPNSNMSSMVVTANGNDSKKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQAVLQAVTAVQTANTPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAGRVGMPGVSAGGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQRDHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI
• Localization: Nuclear
• Specificity: PTBP2 - polypyrimidine tract binding protein 2
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTBP2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PTBP2 Antibody (2D10-B2) - Azide and BSA Free

• brPTB
• FLJ34897
• neural polypyrimidine tract binding protein
• Neural polypyrimidine tract-binding protein
• Neurally-enriched homolog of PTB
• nPTB
• nPTB6
• nPTB7
• nPTB8
• polypyrimidine tract binding protein 2
• polypyrimidine tract-binding protein 2
• PTB-like protein
• PTBPTBLPnPTB5
• splicing regulator

Background

The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PTBP2 Antibody (H00058155-M01)(3)

Publications using H00058155-M01

• Lin JC, Lee YC, Liang YC et al. The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells. Sci Rep 2017-03-09 [PMID: 28276498]
• Liang YC, Lin WC, Lin YJ, Lin JC. The impact of RNA binding motif protein 4-regulated splicing cascade on the progression and metabolism of colorectal cancer cells. Oncotarget 2015-11-10 [PMID: 26506517]
• Xue Y, Zhou Y, Wu T et al. Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol Cell. 2009-12-05 [PMID: 20064465]

Bioinformatics

• Gene Symbol: PTBP2
• Entrez:
  • 58155(Human)
• OMIM:
  • 608449(Human)
• Uniprot:
  • AAH16582(Human)