Protocadherin gamma C3 Antibody

Images

 
Western Blot: Protocadherin gamma C3 Antibody [NBP1-59239] - Sample Type: Human Adult Placenta Antibody Dilution: 1.0 ug/ml
Western Blot: Protocadherin gamma C3 Antibody [NBP1-59239] - 721_B cell lysate, concentration 0.2-1 ug/ml.
Western Blot: Protocadherin gamma C3 Antibody [NBP1-59239] - Analysis of 293T cell lysate. Antibody Dilution: 1.0 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Protocadherin gamma C3 Antibody Summary

Immunogen
Synthetic peptides corresponding to PCDHGC3(protocadherin gamma subfamily C, 3) The peptide sequence was selected from the C terminal of PCDHGC3. Peptide sequence IKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLS.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PCDHGC3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against PCDHGC3 and was validated on Western blot.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for Protocadherin gamma C3 Antibody

  • Cadherin-Like 2
  • PC43
  • PC-43
  • PCDH2
  • PCDH-GAMMA-C3
  • PCDHGC3
  • protocadherin 2
  • Protocadherin 43
  • Protocadherin gamma C3
  • protocadherin gamma subfamily C, 3
  • protocadherin gamma-C3
  • Protocadherin-2
  • protocadherin-43

Background

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. PCDHGC3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PCDHGC3
Entrez
Uniprot