Western blot shows lysates of human serum, mouse serum, and rat serum. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human/Mouse/Rat Properdin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8216) ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Immunogen affinity purified
Reconstitute at 0.2 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Properdin Antibody
Complement Factor P
complement factor properdin
Human Properdin, also known as Complement factor P (CFP), is a 53 kDa secreted glycoprotein that exists in
plasma as dimers, trimers or tetramers. It a positive regulator of the
alternate pathway of complement.
Properdin binds to and stabilizes
the C3- and C5-convertase enzyme complexes and is thought to connect humoral
and cellular immunity. Properdin released from activated neutrophils may play a
major role in pattern recognition, whereas plasma properdin may primarily
stabilize convertase. Properdin deficiency results in higher susceptibility to
bacterial infections. Full-length human Properdin shares 77 % sequence identity
with mouse Properdin.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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