Profilin 2 Antibody

Images

 
Western Blot: Profilin 2 Antibody [H00005217-D01P] - Analysis of PFN2 expression in transfected 293T cell line by PFN2 polyclonal antibody.Lane 1: PFN2 transfected lysate(15 KDa).Lane 2: Non-transfected lysate.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00005217-D01P
    • Availability
      Product Discontinued

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Profilin 2 Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
PFN2 (AAH18049.1, 1 a.a. - 140 a.a.) full-length human protein. MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLALGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
Specificity
This product is specific for Human PFN2 purified MaxPab rabbit polyclonal antibody (D01P) [Gene ID: 5217].
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PFN2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Profilin 2 Antibody

  • D3S1319E
  • PFL
  • profilin 2
  • Profilin II
  • profilin-2

Background

Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals by binding to actin (1:1 ratio) and so affecting the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Highly expressed in skeletal muscle, kidney and brain and less strongly in placenta, heart, liver and lung.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Research Areas for Profilin 2 Antibody (H00005217-D01P)

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Blogs on Profilin 2.

Profiling the Profilin 1 Antibody
Profilin-1, or Pfn-1, is a small actin-binding protein which plays an essential role controlling the growth of microfilaments. Profilin 1 and Profilin 2 have similar biochemical properties but are expressed in different tissues. The Profilin 1 antibod...  Read full blog post.

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Bioinformatics

Gene Symbol PFN2
Uniprot