PRKCDBP Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: PRKCDBP Antibody [NBP2-57897] - Staining of human cell line A-431 shows localization to plasma membrane.

• Reactivity: Hu
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PRKCDBP Antibody - BSA Free Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEALLQMESVA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CAVIN3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
• Application Notes: Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  PRKCDBP Recombinant Protein Antigen (NBP2-57897PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PRKCDBP Antibody - BSA Free

• Cavin-3
• HSRBC
• MGC20400
• protein kinase C, delta binding protein
• sdr-related gene product that binds to c-kinase
• Serum deprivation response factor-related gene product that binds to C-kinase
• SRBCprotein kinase C delta-binding protein

Background

PRKCDBP, also known as Protein kinase C delta-binding protein, is 261 amino acids in length and approximately 27kDa. PRKCDBP is highly expressed in epithelial cells, and is down regulated in lung cancer cell lines and breast cancer cell lines, thus suggesting the possibility of tumor suppressor function. PRKCDBP binds and is phosphorylated by protein kinase C, delta. Current research surrounding PRKCDBP shows a possible connection with ovarian cancer, gastric cancer and lung cancer. PRKCDBP has also been shown to interact with Caveolin 1, Caveolin 3, cMyc, SDPR, and EPS15L1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CAVIN3