Peripherin 2/PRPH2 Antibody - BSA Free

Western Blot: Peripherin 2/PRPH2 Antibody - BSA Free [NBP3-46880] - Mouse eye tissue were subjected to SDS PAGE followed by western blot with (Peripherin 2/PRPH2 antibody) at dilution of 1:1000

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Peripherin 2/PRPH2 Antibody - BSA Free Summary

• Immunogen: peripherin 2(retinal degeneration, slow). (Uniprot# P23942)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PRPH2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 39 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Peripherin 2/PRPH2 Antibody - BSA Free

• AOFMD
• AVMD
• CACD2
• CACD2peripherin 2, homolog of mouse
• DS
• peripherin 2 (retinal degeneration, slow)
• Peripherin 2
• peripherin-2
• PRPH2
• PRPHperipherin, photoreceptor type
• rd2
• RDS
• Retinal degeneration slow protein
• retinal degeneration, slow
• retinal peripherin
• RP7
• Tetraspanin-22
• TSPAN22
• tspan-22
• TSPAN22retinal degeneration, slow (retinitis pigmentosa 7)

Background

The protein encoded by the PRPH2 gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PRPH2