Pellino 1 Antibody

Western Blot: Pellino 1 Antibody [NB100-56672] - Analysis of Pellino 1 (Peli1) in human Ramos lysate (A) and mouse RAW lysate (B) using Pellino 1 antibody at 1:1000.

Immunohistochemistry-Paraffin: Pellino 1 Antibody [NB100-56672] - Analysis of human breast using Pellino 1 antibody at 1:100.

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

Pellino 1 Antibody Summary

• Immunogen: This antibody was developed against KLH-conjugated synthetic peptide corresponding to a portion of amino acids 100-150 of human Pellino 1 (Peli1), Genbank No. NP_065702.2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PELI1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100
  • Western Blot 1:500-1:1000
• Control:

  Pellino 1 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera with PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Alternate Names for Pellino 1 Antibody

• DKFZp686C18116
• MGC50990
• PELI1
• pellino (Drosophila) homolog 1
• pellino homolog 1 (Drosophila)
• Pellino-1
• Pellino-related intracellular-signaling molecule
• PRISM
• protein pellino homolog 1

Background

Pellino 1, also called Peli1, is the mammalian homologue of Pellino, a Drosophila Pelle-interacting protein. Pelle is a serine-threonine kinase through which Toll signaling can occur.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Pellino 1 Antibody (NB100-56672)(2)

Publications using NB100-56672

• Ceppi M, Pereira PM, Dunand-Sauthier I et al. MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc Natl Acad Sci U S A. 2009-02-24 [PMID: 19193853] (WB, Human)
  
  Details:
  WB (human monocyte-derived dendritic cells), Fig. 3B, 4B.
• Choi KC, Lee YS, Lim S et al. Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1. Nat Immunol. 2006-10-01 [PMID: 16951688] (WB, Mouse)

Bioinformatics

• Gene Symbol: PELI1
• Entrez:
  • 57162(Human)
  • 67245(Mouse)