Pellino 1 Antibody (SR2461)

Western Blot: Pellino 1 Antibody (SR2461) [NBP3-27744] - Western blot analysis of Pellino 1 in rat Brain, Jurkat lysates

• Reactivity: Hu, Rt
• Applications: WB, IP
• Clone: SR2461
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

Pellino 1 Antibody (SR2461) Summary

• Description: Novus Biologicals Rabbit Pellino 1 Antibody (SR2461) (NBP3-27744) is a recombinant monoclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant protein of human Pellino 1 (Uniprot #: Q96FA3)
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PELI1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:20
  • Western Blot 1:500-1:1000
• Theoretical MW: 46 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Purity: Affinity purified

Alternate Names for Pellino 1 Antibody (SR2461)

• DKFZp686C18116
• MGC50990
• PELI1
• pellino (Drosophila) homolog 1
• pellino homolog 1 (Drosophila)
• Pellino-1
• Pellino-related intracellular-signaling molecule
• PRISM
• protein pellino homolog 1

Background

Pellino 1 is the mammalian homologue of Pellino, a Drosophila Pelle-interacting protein. Pelle is a serine-threonine kinase through which Toll signaling can occur. Pellino 1 is a scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PELI1